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Unfortunately, there are areas of the tire that cannot be repaired, such as the shoulder and the sidewall. In both of these locations, there is too much flex and movement and a plug-patch will not hold. Also, if the puncture is in the tread but the hole is larger than a quarter inch, it cannot be repaired safely.
Simply so, how much does it cost to fix a tire with a nail in it?
On average, tire puncture repair will cost you between $10 and $20. The repair will involve getting the tire patched. Some tire dealers will repair a punctured tire for free if you purchased your tire from them. It is really a nice service to have at your disposal, and it makes you want to do business with them again.
Correspondingly, how long can you drive with a nail in your tire?
A repair too close to the sidewall may cause a blowout if you hit a curb just right. If the nail is toward the center of the tire, you're in luck because it can be patched. I've driven close to 3 weeks with a nail in the center area of the tread.
Repair of any punctures in the shoulder and sidewall areas are not permitted. This tire has been punctured in the tread area by a screw less than 1/4" in diameter. This tire has been punctured through the shoulder area long enough ago for part of the nail head to have worn away.