Asked by: Aram Moçomedical health brain and nervous system disorders
Can you have too much acetylcholine?
Last Updated: 10th February, 2020
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Then, what happens if you have too much acetylcholine?
Excessive accumulation of acetylcholine (ACh)atthe neuromuscular junctions and synapses causes symptoms ofbothmuscarinic and nicotinic toxicity. These include cramps,increasedsalivation, lacrimation, muscular weakness, paralysis,muscularfasciculation, diarrhea, and blurryvision.
Subsequently, question is, how do you produce more acetylcholine? Choline is an essential nutrient and a building blockofacetylcholine. Foods that are naturally high incholineinclude whole eggs, meats and fish, and whole grains.Studies inlaboratory animals and humans suggest that consumingfoods orsupplements rich in choline may elevate levelsofacetylcholine in the brain.
Then, what happens if you lack acetylcholine?
Deficiencies in acetylcholine can leadtomyasthenia gravis, which is characterized by muscle weakness.Toolittle acetylcholine may also lead to Alzheimer'sdisease;symptoms include a decline in cognitive abilities andmemoryloss.
Does acetylcholine help memory?
Acetylcholine also promotesmemoryformation and consolidation by supporting hippocampaland corticalsynaptic plasticity—the ability for strengtheningorweakening of signaling between neurons over time to shapelearningand memory.