Asked by: Yongli Gabrielamedical health substance abuse
Does buprenorphine cross the placenta?
Last Updated: 11th March, 2020
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Regarding this, is Buprenorphine safe for pregnancy?
Buprenorphine (which is frequently known by its common brand name, Subutex) is a widely used opioid medication considered safe for women during pregnancy. However, little is known about how the dose of buprenorphine prescribed might affect newborn babies.
Additionally, do Opioids cross placenta? All opioids cross the placenta in significant amounts. It is 50% plasma protein-bound and crosses the placenta readily. Maximal uptake by the fetal tissues occurs 2–3 h after a maternal i.m. dose, and this is the time when neonatal respiratory depression is most likely to occur.
Subsequently, one may also ask, does Suboxone affect fetus?
The naloxone part of Suboxone can precipitate opioid withdrawal when abused, making it very risky to both the mother and the fetus during pregnancy. There is a relative lack of data on the safety of this opioid antagonist when used during pregnancy.
Does methadone cross the placenta?
Methadone maintenance, on the other hand, results in increased birth weight and gestational periods. In addition, the fetuses are not exposed to infectious diseases spread by needle sharing, which is common among heroin users. Methadone does enter the placenta and can cause dependence in the fetus.