Asked by: Raul Manukyanmedical health menopause
How do you administer phenytoin IV?
Last Updated: 22nd June, 2020
- Give phenytoin over 30-40 minutes (rate <50mg/minute).
- Ideally, administer undiluted via a syringe pump through a large gauge needle or IV catheter into a large forearm vein.
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Also know, can phenytoin be given IV push?
When treatment with oral phenytoin is not possible, IV DILANTIN can be substituted for oral phenytoin at the same total daily dose. The rate of administration for IV DILANTIN should be no greater than 50 mg per minute in adults and 1 to 3 mg/kg/min (or 50 mg per minute, whichever is slower) in pediatric patients.
Similarly, can phenytoin be given IM? When given by intramuscular injection, phenytoin precipitates out at the injection site and is absorbed slowly and erratically. If phenytoin is administered by intramuscular injection to patients unable to take the drug orally, the dose should be increased by 50% over the previously established oral dose.
Similarly, how do you dilute IV phenytoin?
For administration by intravenous infusion phenytoin injection should be diluted in 50 - 100 ml of normal saline, and the final concentration of phenytoin in the solution should not exceed 10 mg/ml, the infusion mixture should not be refrigerated.
What IV fluid is compatible with phenytoin?
It is concluded that 0.9% sodium chloride and lactated Ringer's injections are suitable diluents for the intravenous administration of phenytoin. Factors other than pH and cosolvent concentration may affect phenytoin stability in dextrose solutions.