Asked by: Kemo Matitoscience chemistry
How is a substrate and its enzyme like a lock and its key?
Last Updated: 14th June, 2020
Click to see full answer.
Similarly one may ask, why is enzyme activity similar to a lock and key?
Explanation: As Vivi explained, enzyme specificity - that is, the enzyme's ability to bind only the correct substrates - comes from having a shape that is nearly perfect for one particular type of molecule. In that sense, the substrate fitting into the enzyme is like a key fitting into a lock.
Additionally, what is the lock and key principle? The lock and key hypothesis states that the substrate fits perfectly into the enzyme, like a lock and a key would. This is in contrast with the induced fit hypothesis, which states that both the substrate and the enzyme will deform a little to take on a shape that allows the enzyme to bind the substrate.
Furthermore, what is the lock and key model of an enzyme?
In 1894, German chemist Emil Fischer proposed the lock and key theory, which states that enzymes have a specific shape that directly correlates to the shape of the substrate. Basically, substrates fit into an enzyme the way a key fits into a lock.
Why does the lock and key analogy fit the linkage between an enzyme and its substrate?
The lock-and-key model portrays an enzyme as conformationally rigid and able to bond only to substrates that exactly fit the active site. The induced fit model portrays the enzyme structure as more flexible and is complementary to the substrate only after the substrate is bound.