Asked by: Cheikhna Jurk
medical health cancer

What does benzamide look like?

Last Updated: 17th April, 2020

verify (what is ?) Benzamide is a whitesolid with the chemical formula ofC6H5C(O)NH2. It is thesimplest amide derivative of benzoic acid. It is slightlysoluble in water, and soluble in many organicsolvents.

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Regarding this, what is benzamide used for?

Benzamide is an intermediate in the Benzoatedegradation via CoA ligation. Benzamides are a class ofchemical compounds derived from Benzamid, the carbonic acid amideof benzoic acid. In psychiatry some substituted benzamidesare therapeutically used as neuroleptics and/orantipsychotics (wikipedia).

Subsequently, question is, how do you make benzamide? Preparation of benzamide by hydrolyzingbenzonitrile with sulfuric acid. 2 g (or 2 ml) of benzonitrile ismixed with 20 ml of 90% sulfuric acid, which is prepared bymixing 25 ml of the concentrated sulfuric acid cautiously withgentle shaking with 5 ml of water.

is benzamide acidic or basic?

Benzoic acid is a weak acid and will reactwith a strong base to form an anion which will dissolve inwater. Aniline is a weak base (whereas benzamide is avery weak base) and will be deprotonated by reaction with astrong acid to form a water soluble cation.

What are benzamide derivatives?

Benzamide Derivative. Benzamidederivatives (MGCD-0103) are a separate class of investigationaldrugs, in clinical development for the treatment of hematologicalmalignancies and solid tumors.

Related Question Answers

Holmes Parra


Is benzamide flammable?

BENZAMIDE reacts with azo and diazo compounds togenerate toxic gases. Forms flammable gases with strongreducing agents.

Mitko Burtea


What is the melting point of benzamide?

Density 1.341 g/cm3
Melting point 127 to 130 °C (261 to 266 °F; 400 to 403 K)
Boiling point 288 °C (550 °F; 561 K)
Solubility in water 13 g/l

Waldina Sanchez Redondo


Is benzamide soluble in ethanol?

Technical Information. Solubility :Soluble in water (13.5 mg/ml at 25° C), methanol (almosttransparency), pyridine (303.03 mg/ml), ethanol (166.67mg/ml), and ethyl ether (slightly).

Angie Sumariva


What is the Colour of amide?

The most commonly discussed amide is ethanamide,CH3CONH2 (old name: acetamide). Notice thatin each case, the name is derived from the acid by replacing the"oic acid" ending by "amide". Methanamide is a liquid atroom temperature (melting point: 3°C), but the otheramides are solid.

Jemina Stephanblome


Is benzoic acid soluble in water?

Benzoic acid or benzene-carbonic-acid is amonobasic aromatic acid, moderately strong, whitecrystalline powder, very soluble in alcohol, ether, andbenzene, but poorly soluble in water (0.3 g of benzoicacid in 100 g of water at 20 °C).

Yerko Barboza


What is the name of c6h5conh2?

An aromatic amide that consists of benzene bearing asingle carboxamido substituent. The parent of the class ofbenzamides. Benzamide is an white solid with the chemical formulaof C6H5C(O)NH2. It is the simplest amide derivative of benzoicacid.

Iba Pedrote


Is benzamide soluble in ether?

Benzamide is not very soluble in ether,benzoic acid is however very soluble in it.

Gildardo Azmani


Is benzoin a mutagen?

Benzoin is synthesized from benzaldehyde in thebenzoin condensation. It is chiral and it exists as a pairof enantiomers: (R)-benzoin and (S)-benzoin.(Wikipedia.

Diosdado Gmelch


Which is more basic aniline or benzamide?

In case of aniline, amino group is directlyattached to the benzene ring. Hence lone pair on nitrogen isinvolved in resonance,thus less available for donation.Thusaniline is weakly basic ,but strong enough thanbenzamide. Hence benzamide is less basic thananiline.

Rommel Valko


Is aniline soluble in NaOH?

Why is aniline insoluble in NaOH? - Quora.Aniline is a benzene ring with an amine group -NH2 attachedto it. Its polarity is so low that interactions between water andthe NH2- group are not sufficient to make the moleculesoluble in water.

Agripina Ryzhkin


What is the name of the functional group that characterizes an alcohol?

A functional group makes up part of a largermolecule. For example, -OH, the hydroxyl group thatcharacterizes alcohols, is an oxygen with a hydrogenattached.

Oliveros Mujitskih


Why is Acetanilide not basic?

Why is aniline more basic thanacetanilide? - Quora. In case of aniline lone pair ofelectrons on nitrogen is engaged in resonance.Hence it is lessavailable for donation.Thus aniline is weakly acidic innature.

Jhoselyn Garisoain


What organic compounds can be oxidized to produce benzoic acid?

It is commercially manufactured by the chemical reactionof toluene (a hydrocarbon obtained from petroleum) with oxygen attemperatures around 200° C (about 400° F) in the presenceof cobalt and manganese salts as catalysts. Pure benzoicacid melts at 122° C (252° F) and is very slightlysoluble in water.

Venelin Lihachev


How is benzamide obtained from benzoic acid?

Benzamide is hydrolyzed to sodium benzoateby boiling with a sodium hydroxide solution. Ammonia is evolved andthe sodium salt of benzoic acid is formed in the solution.The flask is then cooled and the contents acidified withconcentrated hydrochloric acid after transferring to abeaker.