Asked by: Hilal Kopczamedical health infertility
What is the function of cortical granules?
Last Updated: 7th June, 2020
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Keeping this in consideration, what does the cortical granule do?
Cortical granules are regulatory secretory organelles (ranging from 0.2 um to 0.6 um in diameter) found within oocytes and are most associated with polyspermy prevention after the event of fertilization. This exocytosis of cortical granules is known as the cortical reaction.
Secondly, what is cortical granule reaction? Anatomical terminology. The cortical reaction is a process initiated during fertilization by the release of cortical granules from the egg, which prevents polyspermy, the fusion of multiple sperm with one egg.
Likewise, how do cortical granules prevent Polyspermy?
To prevent polyspermy, the zona pellucida, a structure that surrounds mammalian eggs, becomes impermeable upon fertilization, preventing the entry of further sperm. The structural changes in the zona upon fertilization are driven by the exocytosis of cortical granules.
What keeps a second sperm from entering the ovum?
After the sperm enters the cytoplasm of the oocyte (also called ovocyte), the tail and the outer coating of the sperm disintegrate and the cortical reaction takes place, preventing other sperm from fertilizing the same egg. The sperm nucleus then fuses with the ovum, enabling fusion of their genetic material.