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Then, what stimulates the release of secretin?
When hydrochloric acid passes from the stomach into the duodenum, secretin is released into the bloodstream and stimulates the duct cells of the pancreas to secrete water and bicarbonate.
Subsequently, question is, where is CCK produced?
Cholecystokinin, officially called pancreozymin, is synthesized and secreted by enteroendocrine cells in the duodenum, the first segment of the small intestine. Its presence causes the release of digestive enzymes and bile from the pancreas and gallbladder, respectively, and also acts as a hunger suppressant.
Cholecystokinin A receptor (CCKAR) encodes a G-protein-coupled receptor that binds cholecystokinin (CCK) family of peptide hormones and is a major physiological mediator of pancreatic growth and enzyme secretion, smooth muscle contraction of the gallbladder and stomach, and secretion from gastric mucosal cells in the