Asked by: Nidia Josh
medical health cancer

Which is worse CLL or CML?

Last Updated: 12th January, 2020

Is one worse than the other? CML (chronic myelogenous leukemia) and CLL (chronic lymphocytic leukemia) are both cancers that originate from immune-system cells, but that is essentially where their similarities end. Although the term "chronic" is also applied to CML, the disease tends to progress faster than CLL.

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Besides, what is the difference between CLL and CML?

The difference between them is the type of white blood cell that has become cancerous. In CLL, the abnormal cells develop from early blood cells called the lymphoid blood stem cells. In CML, the abnormal leukaemia cells develop from early blood cells called the myeloid blood stem cells. They become myelocytes.

Also, can you have CLL and CML? Chronic lymphocytic leukemia (CLL) and chronic myeloid leukemia (CML) are the most common leukemias of the elderly (>43 year). However, the sequential occurrence of CML followed by CLL in the same patient is extremely rare.

In this regard, which leukemia is most dangerous?

In highly lethal type of leukemia, cancer gene predicts treatment response. Summary: Patients with the most lethal form of acute myeloid leukemia (AML) – based on genetic profiles of their cancers – typically survive for only four to six months after diagnosis, even with aggressive chemotherapy.

What is the life expectancy of someone with CML?

Chronic myeloid leukemia (CML) affects approximately one in 100,000 individuals per year and accounts for 15 percent of all new cases of leukemia in the Western Hemisphere. Before the development of targeted therapy with tyrosine kinase inhibitors (TKIs), the median survival was five to seven years.

Related Question Answers

Henning Dunckelmann


Can I drink alcohol with CLL?

Alcohol use. Excessive alcohol use can damage your liver and other vital organs, including your bone marrow, and limit your future treatment options for CLL. Even moderate alcohol intake can have a suppressive effect on bone marrow function.

Sadrac Quillin


What foods should I avoid with chronic myeloid leukemia?

When following a neutropenic diet, you generally must avoid:
  • all uncooked vegetables.
  • most uncooked fruits, except those with a thick peel like banana or citrus fruits.
  • raw or rare meat.
  • uncooked fish.
  • uncooked or undercooked eggs.
  • most foods from salad bars and deli counters.

Yulieth Ladron


Can CML spread to other organs?

It begins in the blood-forming cells of the bone marrow and then, over time, spreads to the blood. Eventually, the disease spreads to other areas of the body. However, CML can change from slow progressing into a rapidly growing, acute form of leukemia that can spread to almost any organ in the body.

Yongping Heizaga


Does CML run in families?

The risk of getting CML does not seem to be affected by smoking, diet, exposure to chemicals, or infections. And CML does not run in families.

Gulfam Saiago


Is CML painful?

Leukemia cells can also spread into your joints. One symptom of bone metastasis is bone and joint pain, and it's likely to worsen as the disease progresses. Some medications used to treat CML can cause muscle aches, cramps, and weakness.

Kabir Opgenoort


Which leukemia has the best prognosis?

Acute lymphocytic leukemia (ALL)
The 5-year survival rate for children with ALL has greatly increased over time and is now about 90% overall. In general, children in lower risk groups have a better outlook than those in higher risk groups.

Lionel Jonge


What is the life expectancy of a person with leukemia?

Long term survival of leukemia varies greatly, depending upon multiple factors, including type of leukemia and age of the patient. ALL: In general, the disease goes into remission in nearly all children who have it. More than four out of five children live at least five years. The prognosis for adults is not as good.

Denisha Yujenko


How do you know if CLL is progressing?

Disease progression of chronic lymphocytic leukemia
  1. more than 10% weight loss in 6 months.
  2. extreme tiredness.
  3. fever for more than 2 weeks without any signs of infection.
  4. night sweats for longer than 1 month.
  5. bone marrow failure that gets worse and lower numbers of healthy red blood cells (called anemia) or platelets (called thrombocytopenia)

Saloua Tayler


Is leukemia curable if caught early?

Acute leukemia needs to be treated when it is diagnosed, with the goal of inducing a remission (absence of leukemia cells in the body). Acute leukemias can often be cured with treatment. Chronic leukemias are unlikely to be cured with treatment, but treatments are often able to control the cancer and manage symptoms.

Nolan Privrata


What organs does leukemia affect?

Leukemia starts in the soft, inner part of the bones (bone marrow), but often moves quickly into the blood. It can then spread to other parts of the body, such as the lymph nodes, spleen, liver, central nervous system and other organs.

Parker Kafkova


How do AML patients die?

Death in patients with AML may result from uncontrolled infection or hemorrhage. This may happen even after use of appropriate blood product and antibiotic support.

Safiatou Brandsch


Can you die from acute lymphoblastic leukemia?

What are the survival rates for acute lymphoblastic leukemia? About 98% of children with ALL go into remission within weeks after starting treatment. About 90% of those children can be cured. Patients are considered cured after 10 years in remission.

Momna Innes


Can leukemia spread to the brain?

The leukemia cells can spread outside the blood to other parts of the body, including the central nervous system (brain and spinal cord), skin, and gums.

Xinyuan Quentmeier


Why is leukemia so deadly?

They can keep the body from making normal, healthy cells. Eventually, a person will start to lack RBCs that carry oxygen, platelets that prevent easy bleeding, and WBCs that protect the body from diseases. That's because their body is too busy making the leukemic blast cells. The result can be deadly.

Alim LaƱo-Erri


Can MDS go into remission?

MDS, like all blood and bone marrow cancers, can go into remission and then recur. So, in fact, many patients will have recurrent MDS following a stem cell transplant.

Mileydis Jankelevich


Which form of leukemia is more serious?

Chronic lymphocytic leukemia (CLL): This disease develops from partly mature white blood cells called lymphocytes. It begins in the bone marrow but then moves into the blood. There are two types of CLL, one that grows slowly, and another that develops more quickly and is more serious.

Lioudmila Calancha


Is leukemia genetic?

Leukemia is a cancer of the body's bone marrow, which is where your blood cells are made. It's a genetic disease, but most cases aren't thought to be hereditary. This means that while leukemia is caused by mutations in your genes, these genetic abnormalities aren't often inherited from your family.

Sarbjit Eichblatt


What is the best diet for CLL?

Starchy foods such as bread, cereals, rice, pasta and potatoes are a really important part of a healthy diet. Try to choose wholegrain varieties whenever you can. Most people know we should be eating more fruit and vegetables, but most of us still aren't eating the recommended at least 5 portions a day.

Marin Riffi


What is the best drug for CML?

There currently 5 TKIs available for CML:
  • Imatinib (Gleevec). Imatinib was the first targeted therapy approved by the U.S Food and Drug Administration (FDA) for CML in 2001.
  • Dasatinib (Sprycel).
  • Nilotinib (Tasigna).
  • Bosutinib (Bosulif).
  • Ponatinib (Iclusig).