Asked by: Wenlong Ortolanomedical health pharmaceutical drugs
Why allopurinol is not given in acute gout?
Last Updated: 21st April, 2020
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Also to know is, can allopurinol be used in acute gout?
BACKGROUND: Traditionally, allopurinol is not initiated during an acute gout attack to avoid prolonging the painful arthritis. The treating physician determined therapy for the acute gout attack. Standard prophylaxis, with colchicine or nonsteroidal anti-inflammatory drugs, was prescribed.
Likewise, why does allopurinol trigger gout? Allopurinol is used to prevent or lower high uric acid levels in the blood. A high uric acid level can cause gout or gouty arthritis (joint pain and inflammation). Allopurinol is a xanthine oxidase inhibitor that works by decreasing the uric acid produced by the body.
Regarding this, should allopurinol be stopped during acute gout?
Do not start allopurinol during an acute attack of gout Allopurinol should not be started at the time of an acute attack of gout, however, if a patient is already taking it regularly, then it should be continued at the same dose.
Which is better for gout colchicine or allopurinol?
Lesson Summary Colchicine is used for acute flare ups of gout to act as an anti-inflammatory by reducing swelling and pain. Allopurinol is an antihyperuricemic which prevents the production of uric acid. Colchicine should be given in small doses to prevent side effects.