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Why is glycine used in TURP?

Last Updated: 2nd April, 2020

Glycine solution as an irrigating agent during transurethral prostatic resection. The observed plasma glycine increase after TURP correlated well with fall in serum sodium and rise in serum PAP, with the blood loss during and up to 15 min after TURP, and also with the weight of the resected tissue.

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Correspondingly, why is glycine used in urology?

1.5% Glycine Irrigation, USP is useful as an irrigating solution for the urinary bladder because this solution is nonhemolytic, nonelectrolytic or very weakly ionized, and provides a high degree of visibility for urologic procedures requiring endoscopy.

Secondly, what causes TURP syndrome? Absorption of the irrigation fluid (2000 ml or more) may lead to TURP syndrome which causes headaches, anxiety, confusion, dyspnoea, arrhythmia, hypotension and seizures and can be fatal if not treated. The symptoms of TURP are generally caused by an excessive fluid load in circulation.

Just so, why normal saline is not used in TURP?

Electrolyte solutions such as normal saline or Ringer Lactate do least harm when absorbed into the circulation. However they cause dispersion of high frequency current from the resectoscope and hence abandoned. A variety of other irrigating fluids have been in use, each having its own merits and demerits.

Is glycine hypotonic?

Glycine Description The solution is nonelectrolytic, hypotonic and has an osmolarity of 200 mOsmol/liter (calc.); pH 6.0 (4.5 to 6.5).

Related Question Answers

Gihan Sudupe


Is glycine toxic?

Glycine is an inhibitory neurotransmitter and if large amounts are absorbed the patient can develop central nervous system toxicity, which includes transient blindness and encephalopathy. Ammonia toxicity can also result because ammonia is a byproduct of glycine metabolism.

Anarbella Dann


How do you do a TURP?

The resectoscope is inserted into the tip of your penis and extended through your urethra and into the prostate area. Your doctor won't need to make any cuts (incisions) on the outside of your body. Your doctor will use the resectoscope to trim tissue from the inside of your prostate gland, one small piece at a time.

Yixin Llandera


How is TURP syndrome treated?

TURP syndrome: Treatment
  1. Fluid restriction.
  2. Loop diuretics.
  3. Hypertonic saline no faster than 100cc/hr for symptomatic hyponatremia.
  4. Midazolam or phenytoin for seizure activity.
  5. Intubation for airway protection.

Aglaia Brumayr


Can BPH cause hyponatremia?

Syndrome of inappropriate antidiuretic hormone secretion (SIADH) and diuretic therapy are the common causes in the elderly. However, acute urinary retention due to benign prostatic hyperplasia (BPH) resulting in hyponatremia is a rare scenario.

Elaia Meszes


Why is normal saline used for bladder irrigation?

Normal saline solution is often used for continuous irrigation of the bladder following prostatectomy in order to prevent clot retention. There is usually a concern for possible sodium reabsorption and consequent fluid retention. The amount reabsorbed is indeed not significant (p > 0.05).

Azul Leceta


What fluid is used for bladder irrigation?

Normal saline and distilled water are the most commonly used irrigation fluids for PCNL.

Jina Arriero


Why is normal saline used for irrigation?

Normal saline is isotonic and the most commonly used wound irrigation solution due to safety(lowest toxicity) and physiologic factors. A disadvantage is that it does not cleanse dirty, necrotic wounds as effectively as other solutions. Water toxicity may result when excess volumes are used.

Rukhsar Stablein


What is irrigation fluid?

Different types of irrigation fluids can be used: sterile water, glycine, mannitol, and sorbitol. Liquids that do not conduct electricity (sterile water, glycine, mannitol, and sorbitol) are used for monopolar resection. Sterile water has the lowest cost and is used by most urological departments in our country.

Casandra Melendreras


What is irrigation solution?

Your doctor or nurse will use Sodium Chloride Irrigation Solution during surgical procedures for cleansing of tissues, body cavities, wounds or irrigation of a special tube called a catheter which is used to drain your bladder and has been designed to be left in place for a prolonged period of time.

Onesima Kwak


What does irrigation mean in surgery?

Wound Irrigation: Definition. Wound irrigation is the act of flushing a wound with a gentle stream of liquid in order to remove dead or necrotic tissue and other debris. Wound irrigation is used to remove dead tissue, dirt, or debris. This wound needs irrigation.

Nayab Laing


Does a TURP damage the urethra?

Other possible consequences of TURP include urinary tract infections (UTIs) and temporary loss of bladder control (incontinence). And – like with most operations – there is a risk of bleeding that needs to be treated. In rare cases, surgery can cause narrowing of the urethra.

Marton Schochlin


What to expect after a TURP?

For several days after surgery, you may feel burning when you urinate. Your urine may be pink for 1 to 3 weeks after surgery. You also may have bladder cramps, or spasms. Your doctor may give you medicine to help control the spasms.

Deivy Gorig


What are the complications of TURP?

What are the risks of a TURP?
  • Bladder injury.
  • Bleeding.
  • Blood in the urine after surgery.
  • Electrolyte abnormalities.
  • Infection.
  • Loss of erections.
  • Painful or difficult urination.
  • Retrograde ejaculation (when ejaculate goes into the bladder and not out the penis)

Cibeles Caero


Gaylene Coiduras


Is TURP a major surgery?

The most common surgery for BPH is called transurethral resection of the prostate or TURP. During the procedure, surgeons remove the excess prostate tissue through the urethra. A doctor who specializes in the urinary tract does most TURP surgeries. TURP is considered a fairly safe, effective procedure for treating BPH.

Tomeu Grau


Which are the signs symptoms of transurethral resection TUR syndrome?

Symptoms and signs
  • Restlessness.
  • Headache.
  • Nausea and vomiting.
  • Confusion.
  • Visual disturbances.
  • Cerebral edema.
  • Convulsions.
  • Coma.

Nivardo Boomgarden


Does TURP surgery cause impotence?

It is known that a proportion of patients who undergo transurethral resection of the prostate (TURP) will develop erectile dysfunction (ED). Without taking note of the risk factors, TURP is a safe procedure with regard to sexual function.

Geoffrey Nithin


What's a TURP in prostate cancer?

Transurethral resection of the prostate (TURP) is an operation to remove the parts of the prostate gland that are pressing on the urethra.

Violetta Lascurain


What is a bipolar TURP?

Button TURP, also called bipolar cautery vaporization, is a newer, less invasive variation of the procedure. Instead of a wire loop on the end of the scope, the surgeon uses a device with a small, button-shaped tip to vaporize prostate tissue.